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For the novel therapeutic agents, for the patients.

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Faculty of Pharmacy, Kanazawa Univ, Kakuma-machi, Kanazawa 920-1192, Japan 

分子を利用し薬物治療を目指す

We are performing research to identify novel molecular targets in the body which can be applied to develop therapeutic agents. Our research is principally based on pharmacology and pharmacokinetics. The ultimate goal of our research is solely to controbute to the development of pharmacotherapeutics for the patients and to overcome variou diseases.

information


  • July 5, 2017      
    Original paper was accepted:
    Ishimoto T, Nakamichi N, Nishijima H, Masuo Y, Kato Y. Carnitine/organic
    cation transporter OCTN1 negatively regulates activation in murine cultured
    microglial cells. Neurochem Res, in press.

  • May 11-13, 2017
    Dr. Masuo and Mr. Kawanishii (M1) performed presentation in The 32th Annual Meeting of the Academy of Pharmaceutical Science and Technology, Japan (Omiya, Japan). Dr. Masuo winned the best presentation prize.

  • April 24, 2017      
    Original paper was accepted:
    Fujita K, Masuo Y, Yamazaki E, Shibutani T, Kubota Y, Nakamichi N, Sasaki Y, Kato Y. Involvement of the transporters P-gp and BCRP in dermal distribution of the multi-kinase inhibitor regorafenib and its active metabolites. J Pharm Sci 106(9): 2632-2641, 2017.

  • April 17, 2017
    Welcome Party for New Collaborators

  • March 24-27, 2017
    Ms. Komori (B4) performed presentation in The 137th Annual Meeting of the Pharmaceutical Society of Japan (Sendai, Japan).

  • March 22, 2017
    Graduation Ceremony

  • March 13, 2017
    Farewel Party for graduates

  • March 4, 2017
    Original paper was accepted:
    Masuo Y, Nagamori S, Hasegawa A, Hayashi K, Isozumi N, Nakamichi N, Kanai Y, Kato Y. Utilization of Liver Microsomes to Estimate Hepatic Intrinsic Clearance of Monoamine Oxidase Substrate Drugs in Humans. Pharm Res 34(6): 1233-1243, 2017.

  • February 23, 2017
    Original paper was accepted:
    Hashimoto N, Nakamichi N, Yamazaki E, Oikawa M, Masuo Y, Schinkel AH, Kato Y. P-Glycoprotein in skin contributes to transdermal absorption of topical corticosteroids. Int J Pharm 521(1-2):365-373, 2017.

  • February 21-22, 2016
    Graduation Presentation by M2

  • February 17, 2017
    Graduation Presentation by B4 in School of Pharmaceutical Sciences.

  • January 13, 2017
    New comers (3rd year students, School of Pharmacy) joined our laboratory.

  • December 26, 2016
    Laboratory Cleaning and Year-End Party

  • December 16, 2016
    New comers (3rd year students, School of Pharmaceutical Sciences) joined our laboratory.

  • November 29, 2016
    Graduation Presentation by B6

  • November 27, 2016
    Mr. Kawanishi (B4) will perform presentation in The 128th Annual Meeting of Hokuriku Branch in the Pharmaceutical Society of Japan (Kanazawa, Japan).

  • November 17-18, 2016
    Dr. Nakamichi and Mr. Ishimoto (D3) will perform presentation in The 38th Symposium on Interaction of Biomembranes and Drugs (Nagoya, Japan).

  • October 13-15, 2016
    Dr. Masuo, Mr. Taguchi (D3), Ms. Ohba (M2), Ms. Futatsugi (M2), Ms. Ainaka (M1), Ms. Hasegawa (B5), Ms. Yamazaki (B5) and Ms. Seba (B4) performed presentation in 31th Annual Meeting of JSSX (Matsumoto, Japan).

  • July 26, 2016
    Original paper was accepted:
    Nakamichi N, Ishimoto T, Yamauchi Y, Masuo Y, Kato Y. Screening to Identify Multidrug Resistance-Associated Protein Inhibitors with Neuroblastoma-Selective Cytotoxicity. Biol Pharm Bull 39(10): 1638-1645, 2016.

  • July 3-5, 2016
    Dr. Nakamichi and Mr. Ishimoto (D3) performed presentation in the CINP 30th World Congress of Neuropsychopharmacology (Seoul).

  • April 30, 2016
    Original paper was accepted:
    Futatsugi A, Masuo Y, Kawabata S, Nakamichi N, Kato Y. L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides. J Pharm Pharmacol 68(9): 1160-1169, 2016.

  • April 20, 2016
    Original paper was accepted:
    Taguchi T, Masuo Y, Kogi T, Nakamichi N, Kato Y. Characterization of long-lasting Oatp inhibition by typical inhibitor cyclosporine A and in vitro-in vivo discrepancy in its drug interaction potential in rats. J Pharm Sci 105(7):2231-2239, 2016.

  • April 19, 2016
    Welcome Party for New Collaborators




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ナビゲーション

Laboratory of Molecular Pharmacotherapeuticsビルダークリニック

Faculty of Pharmcy,
Kanazawa University,
Kakuma-machi,
Kanazawa 920-1102, Japan
bunyaku@p.kanazawa-u.ac.jp



安全創薬研究 グループへリンク

金沢大学薬学類・ 創薬科学類へリンク




金沢大学薬学類・ 創薬科学類へリンク