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論文リスト

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大場　正志（OHBA, Masashi）

研究論文（1985 年以降）

  1. T. Fujii and M. Ohba, Quinolizidines. X. Stereospecific Syntheses of (ｱ)-9-Demethylpsychotrine and (ｱ)-10-Demethylpsychotrine, Chem. Pharm. Bull., 33, 144 (1985).
  2. T. Fujii, M. Ohba, K. Yoneyama, and H. Kizu, Lactams. XXII. Preparation of the Enantiomers of 6-Ethoxy-3-ethyl-2,3,4,5-tetrahydro-4-pyridineacetic Acid Ethyl Ester, Chem. Pharm. Bull., 33, 358 (1985).
  3. T. Fujii and M. Ohba, Quinolizidines. XI. Structure Determination of the Alangium Alkaloid Desmethylpsychotrine through Synthetic Incorporation of Ethyl Cincholoiponate into (+)-9-Demethylpsychotrine, Chem. Pharm. Bull., 33, 583 (1985).
  4. T. Fujii, M. Ohba, and H. Suzuki, Quinolizidines. XII. Synthetic Incorporation of Ethyl Cincholoiponate into a Tricyclic Intermediate Adaptable to Chiral Syntheses of the 10-Hydroxy-9-methoxybenzo[a]quinolizidine-Type Alangium Alkaloids, Chem. Pharm. Bull., 33, 1023 (1985).
  5. T. Fujii, M. Ohba, S. Yoshifuji, and S. Akiyama, Lactams. XXIII. Thermal cisﾐtrans Isomerization of the 5-Ethyl-2-oxo-4-piperidineacetic Acid System: Effect of an N-Substituent, Chem. Pharm. Bull., 33, 1062 (1985).
  6. C. Kan-Fan, R. Freire, H.-P. Husson, T. Fujii, and M. Ohba, (ﾐ)-9-Demethyltubulosine, an Alkaloid from Alangium vitiense (A. Gray) Baillon (Alangiaceae), Heterocycles, 23, 1089 (1985).
  7. T. Fujii, M. Ohba, and S. Akiyama, Lactams. XXIV. Alkaline Hydrolysis of 1-Benzyl-2-piperidone Derivatives: Application to cisﾐtrans Isomerization of the 5-Ethyl-2-oxo-4-piperidineacetic Acid System, Chem. Pharm. Bull., 33, 1716 (1985).
  8. T. Fujii, H. Kogen, S. Yoshifuji, and M. Ohba, Quinolizidines. XIII. Syntheses of (ｱ)- and (ﾐ)-Alangimarckines, Chem. Pharm. Bull., 33, 1946 (1985).
  9. T. Fujii, Y. Takai, M. Ohba, H. Kogen, and M. Oki, Lactams. XXV. Reassignments of the C=C and C=O Stretching Vibrations in Six-Membered a,b-Unsaturated Lactams, Chem. Pharm. Bull., 33, 2697 (1985).
  10. M. Ohba, M. Hayashi, and T. Fujii, Quinolizidines. XIV. A Racemic Synthesis of 9-Demethyltubulosine, an Alkaloid Isolated from Alangium vitiense, Chem. Pharm. Bull., 33, 3724 (1985).
  11. T. Fujii and M. Ohba, Quinolizidines. XV. A Racemic Synthesis of 10-Demethyltubulosine, an Alkaloid from Alangium lamarckii, Chem. Pharm. Bull., 33, 4314 (1985).
  12. T. Fujii and M. Ohba, Quinolizidines. XVI. Chiral Syntheses of 9-Demethylcephaeline and 10-Demethylcephaeline, Chem. Pharm. Bull., 33, 5264 (1985).
  13. T. Fujii, M. Ohba, and S. Akiyama, Quinolizidines. XVII. A New Access to 9,10-Dimethoxy- and 8-Hydroxy-9,10-dimethoxybenzo[a]quinolizidine-Type Alangium Alkaloids from 3-Acetylpyridine, Chem. Pharm. Bull., 33, 5316 (1985).
  14. T. Fujii, M. Ohba, M. Tsuchida, K. Saito, Y. Hirano, and J. Sakaguchi, Lactams. XXVI. Regioselectivity in the Mercuric AcetateﾐEdetic Acid Oxidation of the Ethyl 1-(2-Aryl-2-hydroxyethyl)-3-ethyl-4-piperidineacetate System: Enhancement by a Benzyloxy Group in the Aryl Moiety and by the 3,4-cis Configuration, Chem. Pharm. Bull., 34, 496 (1986).
  15. T. Fujii, M. Ohba, H. Hatakeyama, C. Kan-Fan, and H.-P. Husson, Synthesis and Absolute Configuration of the Alangium vitiense Alkaloid (ﾐ)-9-Demethyltubulosine, Heterocycles, 24, 317 (1986).
  16. T. Fujii, M. Ohba, A. Yonezawa, J. Sakaguchi, S. K. Chattopadhyay, D. J. Slatkin, P. L. Schiff, Jr., and A. B. Ray, Racemic and Chiral Syntheses of the Alangium Alkaloid Alancine, Heterocycles, 24, 345 (1986).
  17. T. Fujii, M. Ohba, K. Yoneyama, H. Kizu, and S. Yoshifuji, Quinolizidines. XVIII. Syntheses of (ﾐ)- and (+)-Ankorines through a Lactim Ether Route, Chem. Pharm. Bull., 34, 669 (1986).
  18. T. Fujii, M. Ohba, T. Tachinami, H. Miyajima, M. Koch, and E. Seguin, Structure Determination of the Ochrosia Alkaloid Ochropposinine: Syntheses of (ｱ)- and (ﾐ)-Ochropposinine, Heterocycles, 24, 1215 (1986).
  19. T. Fujii, M. Ohba, and H. Hatakeyama, Quinolizidines. XIX. Synthesis of (ﾐ)-9-Demethyltubulosine, Chem. Pharm. Bull., 35, 2355 (1987).
  20. T. Fujii, M. Ohba, E. Ali, H. Suzuki, and J. Sakaguchi, Quinolizidines. XX. Racemic and Chiral Syntheses of the Alangium Alkaloids 9-Demethylprotoemetinol and 10-Demethylprotoemetinol, Chem. Pharm. Bull., 35, 2755 (1987).
  21. T. Fujii, M. Ohba, A. Yonezawa, and J. Sakaguchi, Quinolizidines. XXI. Syntheses of (ｱ)- and (ﾐ)-Alancines, Chem. Pharm. Bull., 35, 3470 (1987).
  22. T. Fujii, M. Ohba, and J. Sakaguchi, Quinolizidines. XXII. An Extension of the ﾒ3-Acetylpyridine Routeﾓ to the Syntheses of 9-Hydroxy-10-methoxy- and 10-Hydroxy-9-methoxybenzo[a]quinolizidine-Type Alangium Alkaloids, Chem. Pharm. Bull., 35, 3628 (1987).
  23. T. Fujii, M. Ohba, K. Shimohata, and S. Yoshifuji, Quinolizidines. XXIII. An Alternative Synthetic Route to Benzo[a]quinolizidine-Type Alangium Alkaloids from Ethyl Cincholoiponate, Heterocycles, 26, 2949 (1987).
  24. T. Fujii and M. Ohba, Quinolizidines. XXIV. Syntheses of Ankorine Congeners in Different Oxidation States, Chem. Pharm. Bull., 36, 2665 (1988).
  25. T. Fujii, M. Ohba, and M. Sakari, Syntheses of (1'R)-1'-Methyl-cis-zeatin and Its 9-b-D-Ribofuranoside, Heterocycles, 27, 2077 (1988).
  26. E. Fontes, P. A. Heiney, M. Ohba, J. N. Haseltine, and A. B. Smith, III, Molecular Disorder in Columnar-Phase Discotic Liquid-Crystal Strands, Phys. Rev. A, 37, 1329 (1988).
  27. A. B. Smith, III, B. D. Dorsey, M. Ohba, A. T. Lupo, Jr., and M. S. Malamas, Preparation, Reactivity, and Spectral Properties of 1,3-Dioxin Vinylogous Esters: Versatile b-Ketovinyl Cation Equivalents, J. Org. Chem., 53, 4314 (1988).
  28. W. K. Lee, B. A. Wintner, E. Fontes, P. A. Heiney, M. Ohba, J. N. Haseltine, and A. B. Smith, III, Reentrant Isotropic Phase in a Discotic Liquid Crystal Mixture, Liq. Crystals, 4, 87 (1989).
  29. A. B. Smith, III, A. T. Lupo, Jr., M. Ohba, and K. Chen, Total Synthesis of (+)-Hydroxyjatrophone A and (+)-Hydroxyjatrophone B, J. Am. Chem. Soc., 111, 6648 (1989).
  30. T. Fujii, M. Ohba, T. Tachinami, T. Ohashi, M. Koch, and E. Seguin, Structure and Absolute Configuration of the Ochrosia Alkaloid Ochromianine: Syntheses of (ｱ)- and (ﾐ)-Ochromianine, Heterocycles, 29, 1037 (1989).
  31. T. Fujii, M. Ohba, and N. Sasaki, Quinolizidines. XXVI. A Synthesis of (ｱ)-Deplancheine, Chem. Pharm. Bull., 37, 2822 (1989).
  32. T. Fujii, M. Ohba, T. Tachinami, and H. Miyajima, Quinolizidines. XXVII. Racemic and Chiral Syntheses of the Neisosperma and Ochrosia Alkaloid Ochropposinine, Chem. Pharm. Bull., 38, 1200 (1990).
  33. M. Ohba, T. Fujii, A. Evidente, G. Surico, and N. S. Iacobellis, 1'-Methylzeatin and Its 9-b-D-Ribofuranoside: The Carbon-13 Nuclear Magnetic Resonance Spectra Revisited, Heterocycles, 31, 599 (1990).
  34. T. Fujii, M. Ohba, M. Sakari, and S. Matsubara, Purines. XLV. Syntheses and Cytokinin Activities of the Cis Isomers of (1'R)-1'-Methylzeatin and Its 9-b-D-Ribofuranoside, Chem. Pharm. Bull., 38, 2702 (1990).
  35. T. Fujii, M. Ohba, T. Tachinami, and T. Ohashi, Quinolizidines. XXVIII. Racemic and Chiral Syntheses of Ochromianine, an Indoloquinolizidine Alkaloid from Neisosperma miana, Chem. Pharm. Bull., 39, 75 (1991).
  36. M. Ohba, T. Ohashi, and T. Fujii, Quinolizidines. XXIX. Preparation of (ﾐ)-Dihydrocorynantheol, Heterocycles, 32, 319 (1991).
  37. M. Ohba, T. Mukaihira, and T. Fujii, Synthesis of 5-Arylthio-3-methyl-L-histidine, a Model for the Starfish Alkaloid Imbricatine, Heterocycles, 33, 21 (1992).
  38. T. Fujii, M. Ohba, T. Haneishi, S. Matsubara, A. H. A. Farooqi, and Y. N. Shukla, Synthesis and Absolute Configuration of the Green Alga Cytokinin 2-Hydroxy-1'-methylzeatin, Heterocycles, 34, 21 (1992).
  39. A. Evidente, G. Piccialli, A. Sisto, M. Ohba, K. Honda, and T. Fujii, Syntheses of cis-Zeatin and Its 9-(2-Deoxy-b-D-ribofuranosyl) Derivative: A Novel Synthetic Route to the Side Chain at C(6), and Cytokinin Activity, Chem. Pharm. Bull., 40, 1937 (1992).
  40. M. Ohba, Y. Shinbo, M. Toda, and T. Fujii, Quinolizidines. XXX. A Ready Access to the Dibenzo[a,f]quinolizidine Ring System from 1,2,3,4-Tetrahydroquinoline, Chem. Pharm. Bull., 40, 2543 (1992).
  41. M. Ohba, Y. Shinbo, T. Ohashi, M. Toda, and T. Fujii, Quinolizidines. XXXI. A Synthesis of the Dibenzo[a,h]quinolizidine Ring System: An Application of the Mercuric AcetateﾐEdetic Acid Oxidation Method to 1,2,3,4-Tetrahydroisoquinoline, Heterocycles, 34, 1857 (1992).
  42. T. Fujii, M. Ohba, and T. Ohashi, Quinolizidines. XXXII. A Chiral Synthesis of 3,4,5,6-Tetrahydro-17-hydroxycorynanium, the Zwitterionic Structure Assigned to an Alkaloid from Aspidosperma marcgravianum, Tetrahedron, 49, 1879 (1993).
  43. T. Fujii, M. Ohba, H. Kawamura, T. Haneishi, and S. Matsubara, Purines. LV. Syntheses and Cytokinin Activities of Some Adenine and Adenosine Derivatives Related to 1'-Methylzeatin, Chem. Pharm. Bull., 41, 1362 (1993).
  44. T. Fujii, M. Ohba, H. Kawamura, Y. Nakashio, K. Honda, and S. Matsubara, Purines. LXII. Both Enantiomers of N6-(1,3-Dimethyl-2-butenyl)adenine and Their 9-b-D-Ribofuranosides: Synthesis and Cytokinin Activity, Chem. Pharm. Bull., 42, 1045 (1994).
  45. T. Fujii, T. Saito, J. Chikazawa, M. Ohba, and T. Date, Model Experiments for Acetylation of the Marine Sponge Purines Agelasimine-A and Agelasimine-B, Heterocycles, 38, 733 (1994).
  46. M. Ohba, S. Seto, T. Fujii, M. V. Sargent, and D. Arbain, Absolute Stereochemistry of the Pentacyclic Quaternary Indole Alkaloid Ophiorrhizine: Synthetic Incorporation of Cincholoipon Ethyl Ester into (ﾐ)-Ophiorrhizine, Heterocycles, 38, 1741 (1994).
  47. M. Ohba, T. Mukaihira, and T. Fujii, Preparatory Study for the Synthesis of the Starfish Alkaloid Imbricatine. Syntheses of 5-Arylthio-3-methyl-L-histidine, Chem. Pharm. Bull., 42, 1784 (1994).
  48. M. Ohba, T. Haneishi, and T. Fujii, Stereoselective Syntheses of cis- and trans-Hexahydrocyclopenta[c]pyran-3(1H)-ones, Heterocycles, 38, 2253 (1994).
  49. S. Matsubara, T. Fujii, and M. Ohba, Cytokinin Activities of 1'-Methyl Derivatives of Zeatin and N6-(D2-Isopentenyl)adenine and of Their 9-b-D-Ribofuranosides in Lettuce Seed Germination, Sci. Rep. Kyoto Pref. Univ., 45, 1 (1994).
  50. T. Fujii, M. Ohba, N. Fukui, and T. Date, Structure Determination of a Geometric Isomer of 2-Acetyl-1,2,3,4-tetrahydro-6,7-dimethoxy-1-(2-methylpropylidene)isoquinoline, Heterocycles, 39, 133 (1994).
  51. T. Fujii, T. Saito, J. Chikazawa, Y. Nakamura, and M. Ohba, Purines. LXV. Preparatory Study for the Syntheses of the Marine Sponge Purines Agelasimines-A and -B: Synthesis and Acetylation of Their N(7)-Benzyl Analogues, Chem. Pharm. Bull., 42, 2461 (1994).
  52. M. Ohba, T. Haneishi, and T. Fujii, Syntheses of Several Cyclopentano-Monoterpene Lactones Using 1,3-Dioxin Vinylogous Ester, Chem. Pharm. Bull., 43, 26 (1995).
  53. T. Fujii, M. Ohba, and S. Seto, Quinolizidines. XXXIII. A Chiral Synthesis of (ﾐ)-Ophiorrhizine, a Pentacyclic Quaternary Indole Alkaloid from Ophiorrhiza major RIDL, Chem. Pharm. Bull., 43, 49 (1995).
  54. M. Ohba, N. Kawase, T. Fujii, K. Aoe, K. Okamura, R. Fathi-Afshar, and T. M. Allen, Racemic Syntheses of Agelasimine-A and Agelasimine-B, Bicyclic Diterpenoids from the Marine Sponge Agelas mauritiana, Tetrahedron Lett., 36, 6101 (1995).
  55. M. Ohba, N. Kawase, and T. Fujii, Acetylations of (ｱ)-Agelasimine-A and (ｱ)-Agelasimine-B: A Racemic Synthesis of Purino-Diterpene Derived from Anti-Microbial Metabolites of Agelas mauritiana, Heterocycles, 41, 2661 (1995).
  56. M. Ohba, M. Imasho, and T. Fujii, Syntheses of L-Phenylalanine Derivatives Containing a Sulfur Substituent at the 2-Position, Heterocycles, 42, 219 (1996).
  57. M. Ohba, T. Haneishi, and T. Fujii, Synthesis of (ｱ)-(4aa,6a,7a,7aa)-Hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-3(1H)-one, a Structure Common to Abelialactone, Aglykon A1, and Isoboonein, Chem. Pharm. Bull., 44, 525 (1996).
  58. M. Ohba, N. Kawase, and T. Fujii, Total Syntheses of (ｱ)-Agelasimine-A, (ｱ)-Agelasimine-B, and (ｱ)-Purino-diterpene and the Structure of Diacetylagelasimine-A, J. Am. Chem. Soc., 118, 8250 (1996).
  59. M. Ohba, H. Kubo, T. Fujii, H. Ishibashi, M. V. Sargent, and D. Arbain, Synthesis and Absolute Configuration of (ﾐ)-Normalindine, Tetrahedron Lett., 38, 6697 (1997).
  60. M. Ohba, K. Iizuka, H. Ishibashi, and T. Fujii, Syntheses and Absolute Configurations of the Marine Sponge Purines (+)-Agelasimine-A and (+)-Agelasimine-B, Tetrahedron, 53, 16977 (1997).
  61. H. Ishibashi, M. Higuchi, M. Ohba, and M. Ikeda, Effect of Temperature on 5-Endo- and 4-Exo-Trig Radical Cyclizations of N-Vinylic a-Halo Amides, Tetrahedron Lett., 39, 75 (1998).
  62. M. Ohba, H. Kubo, S. Seto, T. Fujii, and H. Ishibashi, A Straightforward Preparation of Chiral 5-(Aminomethyl)oxazole Derivatives from a-Amino Esters and a-Lithiated Isocyanides, Chem. Pharm. Bull., 46, 860 (1998).
  63. M. Ohba, Y. Nishimura, M. Imasho, T. Fujii, J. Kubanek, and R. J. Andersen, Chiral Synthesis of Tri-O-methylimbricatine, an Etherified Derivative of the Starfish Alkaloid Imbricatine, Tetrahedron Lett., 39, 5999 (1998).
  64. M. Ohba, M. Imasho, and T. Fujii, Synthetic Studies on the Starfish Alkaloid Imbricatine. Construction of an ent-Imbricatine Framework, Chem. Pharm. Bull., 47, 83 (1999).
  65. H. Ishibashi, M. Inomata, M. Ohba, and M. Ikeda, Stereoselective Radical Cascade Approach to Benzo[a]quinolizidines, Tetrahedron Lett., 40, 1149 (1999).
  66. M. Ohba, Y. Nishimura, M. Kato, and T. Fujii, Synthetic Studies on the Starfish Alkaloid Imbricatine. A Chiral Synthesis of Tri-O-methylimbricatine, Tetrahedron, 55, 4999 (1999).
  67. H. Ishibashi, M. Maeki, J. Yagi, M. Ohba, and T. Kanai, A Modification of the Asymmetric Dihydroxylation Approach to the Synthesis of (S)-2-Arylpropanoic Acids, Tetrahedron, 55, 6075 (1999).
  68. M. Ohba, H. Kubo, and H. Ishibashi, A Chiral Synthesis of the Strychnos and Ophiorrhiza Alkaloid Normalindine, Tetrahedron, 56, 7751 (2000).
  69. M. Ohba, R. Izuta, and E. Shimizu, A New Access to Cyclopenta[c]pyridine Ring System: Syntheses of (ﾐ)-Plectrodorine and (+)-Oxerine, Tetrahedron Lett., 41, 10251 (2000).

　

総　説

  1. T. Fujii, M. Ohba, and S. Yoshifuji, Chiral Syntheses of Benzo[a]quinolizidine-Type Alangium Alkaloids, Heterocycles, 27, 1009 (1988).
  2. T. Fujii, T. Itaya, and M. Ohba, 1'-Methyl-trans-zeatin and Its Analogues: Their Occurrence, Chemistry and Synthesis, and Cytokinin Activity, Heterocycles, 46, 659 (1997).
  3. T. Fujii and M. Ohba, Racemic and Chiral Syntheses of Some Indolo[2,3-a]quinolizidine Alkaloids through a ﾒLactim Ether Route,ﾓ Heterocycles, 47, 525 (1998).

　

著　書

  1. T. Fujii and M. Ohba, Ipecac Alkaloids and b-Carboline Congeners, ﾒThe Alkaloids,ﾓ Vol. 22, ed. by A. Brossi, Academic Press, New York, Chapter 1 (1983).
  2. T. Fujii and M. Ohba, The Ipecac Alkaloids and Related Bases, ﾒThe Alkaloids,ﾓ Vol. 51, ed. by G. A. Cordell, Academic Press, San Diego, Chapter 3 (1998).

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